Supported by a Wellcome Trust Public Engagement grant (2006-2008) in the History of Medicine to Professor Tilli Tansey (QMUL) and Professor Leslie Iversen (Oxford), the History of Modern Biomedicine Research Group at Queen Mary, University of London presents a series of podcasts on the history of neuroscience featuring eminent people in the field: From 1975 to 1995, Professor Moncada worked at the Wellcome Research Laboratories, first as Head of Prostaglandin Research and then as Director of Research. He described the structure of prostacyclin, which acts as an effective vasodilator and also prevents blood platelets from clumping. In 1980 came the discovery by Robert Furchgott of ' endothelium-derived relaxing factor' (EDRF) which causes smooth muscle in the vessel walls to relax. Moncada and his team showed that EDRF was, in fact, Nitric oxide, which has since become appreciated as a neurotransmitter, a modulator of inflammation and a sensor of cellular distress as well as a regulato
